TRPV1 Recombinant Rabbit Monoclonal Antibody [PSH20-38] (HA724149)

UNIPROT #

Q704Y3

PROTEIN NAME

TRPV1

SYNONYMS

Capsaicin receptor antibody;DKFZp434K0220 antibody;osm 9 like TRP channel 1 antibody;Osm-9-like TRP channel 1 antibody;OTRPC1 antibody;Transient receptor potential cation channel subfamily V member 1 antibody;TRPV 1 antibody;Trpv1 antibody;TRPV1_HUMAN antibody;Vanilloid receptor 1 antibody;Vanilloid receptor subtype 1 antibody;VR 1 antibody;VR1 antibody

SUBCELLULAR LOCATION

Postsynaptic cell membrane, Cell projection, dendritic spine membrane, Cell membrane.

FUNCTION

The transient receptor potential cation channel subfamily V member 1 (TRPV1), also known as the capsaicin receptor and the vanilloid receptor 1, is a protein that, in humans, is encoded by the TRPV1 gene. It was the first isolated member of the transient receptor potential vanilloid receptor proteins that in turn are a sub-family of the transient receptor potential protein group. This protein is a member of the TRPV group of transient receptor potential family of ion channels. Fatty acid metabolites with affinity for this receptor are produced by cyanobacteria, which diverged from eukaryotes at least 2 billion years ago. The function of TRPV1 is detection and regulation of body temperature. In addition, TRPV1 provides a sensation of scalding heat and pain (nociception). In primary afferent sensory neurons, it cooperates with TRPA1 (a chemical irritant receptor) to mediate the detection of noxious environmental stimuli.