Skip to content

Contact

(857) 353-6600

orders@huabio.com

SLC12A2 / NKCC1 Recombinant Rabbit Monoclonal Antibody [PSH23-65] (HA724390)

Price: Regular price $385.00

Unit price per 

Product size

Bulk Order Quote   |   Customization Request

Catalog# HA724390

Rabbit Monoclonal to SLC12A2 / NKCC1

Tested for

  • WB

  • IF-Cell

  • IHC-Fr

  • IHC-P

  • FC(Intra)

  • IP

Reacts with

  • Human

  • Mouse

  • Rat

Recombinant production enables lot-to-lot consistency and is animal-cruelty-free

Safety datasheet

Select your chosen country/region

COA DOWNLOAD

Specifications

Product Type

Recombinant Rabbit monoclonal primary

Product Name

SLC12A2 / NKCC1 Recombinant Rabbit Monoclonal Antibody [PSH23-65] (HA724390)

Immunogen

Recombinant protein within mouse slc12a2 / nkcc1 aa 101-279.

Host

Rabbit

Positive Control

COLO205 (Human colon adenocarcinoma cells) cell lysate, HT-29 (Human colorectal adenocarcinoma cells) cell lysate, HeLa (Human cervical adenocarcinoma cells) cell lysate, NIH/3T3 (Mouse fibroblasts) cell lysate, Mouse cerebellum tissue lysate, Mouse brain tissue lysate, Mouse colon tissue lysate, Mouse small intestine tissue lysate, Rat cerebellum tissue lysate, Rat brain tissue lysate.

Conjugation

Unconjugated

Clonality

Monoclonal

Clone Number

PSH23-65

APPLICATION DILUTION

  • WB

  • 1:5,000

  • IF-Cell

  • 1:500

  • IHC-Fr

  • 1:500

  • IHC-P

  • 1:5,000

  • FC(Intra)

  • 1:1,000

  • IP

  • 1-2μg/sample

PROPERTIES

Form

Liquid

Storage Condition

Shipped at 4℃. Store at +4℃ short term (1-2 weeks). It is recommended to aliquot into single-use upon delivery. Store at -20℃ long term.

Storage Buffer

1*PBS (pH7.4), 0.1% BSA, 40% Glycerol, 0.2% Proclean 950.

Concentration

1ug/ul

Purification

Protein A affinity purified.

Molecular Weight

Predicted band size: 131 kDa

Isotype

IgG

TARGET

UNIPROT #

P55011

PROTEIN NAME

SLC12A2 / NKCC1

SYNONYMS

Solute carrier family 12 member 2;Basolateral Na-K-Cl symporter;Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 2 (BSC2);Na-K-2Cl cotransporter 1 (hNKCC1);SLC12A2;NKCC1

SUBCELLULAR LOCATION

Basolateral cell membrane.

FUNCTION

The Na–K–Cl cotransporter (NKCC) is a transport protein that aids in the secondary active transport of sodium, potassium, and chloride into cells. In humans there are two isoforms of this membrane transport protein, NKCC1 and NKCC2, encoded by two different genes (SLC12A2 and SLC12A1 respectively). Two isoforms of the NKCC1/Slc12a2 gene result from keeping (isoform 1) or skipping (isoform 2) exon 21 in the final gene product. NKCC1 is widely distributed throughout the human body; it has important functions in organs that secrete fluids. In contrast, NKCC2 is found specifically in the kidney, where it extracts sodium, potassium, and chloride from the urine so they can be reabsorbed into the blood.

Close (esc)

Popup

Use this popup to embed a mailing list sign up form. Alternatively use it as a simple call to action with a link to a product or a page.

Age verification

By clicking enter you are verifying that you are old enough to consume alcohol.

Enter

Search

Main menu

Your cart is currently empty.
Shop now