RPL10A Recombinant Rabbit Monoclonal Antibody [JE64-41] (HA721098)

UNIPROT #

P62906

PROTEIN NAME

RPL10A

SYNONYMS

60S ribosomal protein L10a antibody;CSA 19 antibody;CSA-19 antibody;CSA19 antibody;L10A antibody;NEDD 6 antibody;NEDD-6 antibody;NEDD6 antibody;neural precursor cell expressed developmentally down regulated protein 6 antibody;Neural precursor cell expressed developmentally down-regulated protein 6 antibody;Protein NEDD6 antibody;Ribosomal protein L10a antibody;RL10A_HUMAN antibody;rpl10a antibody

SUBCELLULAR LOCATION

Cytosol, cytosolic large ribosomal subunit, cytosolic ribosome, extracellular exosome, nucleus, focal adhesion, membrane, polysomal ribosome.

FUNCTION

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L1P family of ribosomal proteins. It is located in the cytoplasm. The expression of this gene is downregulated in the thymus by cyclosporin-A (CsA), an immunosuppressive drug. Studies in mice have shown that the expression of the ribosomal protein L10a gene is downregulated in neural precursor cells during development. This gene previously was referred to as NEDD6 (neural precursor cell expressed, developmentally downregulated 6), but it has been renamed RPL10A (ribosomal protein 10a). As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.