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Rat Renin, C-His Tag Protein (HA211446)

Price: Regular price $139.00

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Catalog# HA211446

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  • Rat

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Product Details

Product Type

Protein

Product Name

Rat Renin, C-His Tag Protein (HA211446)

Predicted molecular mass

43.1 kD

Protein construction description

A DNA sequence encoding the rat Renin protein (P08424) (Ala 27-Arg 402) was expressed with a His tag at the C-terminus.

Accession

P08424

Protein construction

Renin (27-402) | His

Source

HEK293

Bio Activity

Testing in progress.

Purity

>95% as determined by SDS-PAGE.

Endotoxin

Less than 1.0 EU per μg by the LAL method.

Formulation

Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4, 5% Trehalose, 5% mannitol.

Species

Rat

Background

Renin, also known as an angiotensinogenase, is an aspartic protease protein and enzyme secreted by the kidneys that participates in the body's renin-angiotensin-aldosterone system (RAAS)—also known as the renin-angiotensin-aldosterone axis—that increases the volume of extracellular fluid (blood plasma, lymph, and interstitial fluid) and causes arterial vasoconstriction. Thus, it increases the body's mean arterial blood pressure. Renin is not commonly referred to as a hormone, although it has a receptor, the (pro)renin receptor, also known as the renin receptor and prorenin receptor, as well as enzymatic activity with which it hydrolyzes angiotensinogen to angiotensin I.

Usage Guide

Shipping

In general, recombinant proteins are provided as lyophilized powder which are shipped with blue ice. Bulk packages of recombinant proteins are provided as frozen liquid which are shipped with dry ice.

Storage

Please avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃ It is recommended that aliquot the reconstituted solution to minimize freeze-thaw cycles.

Reconstitution

Reconstitute at 250 μg/ml in sterile water.

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