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p38 delta / MAPK13 Rabbit Polyclonal Antibody (HA500582)

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Catalog# HA500582

Rabbit Polyclonal to p38 delta / MAPK13

Tested for

  • WB

Reacts with

  • Human

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Specifications

Product Type

Rabbit polyclonal primary

Product Name

p38 delta / MAPK13 Rabbit Polyclonal Antibody (HA500582)

Immunogen

Synthetic peptide within human p38 delta / mapk13 aa 251-300.

Specificity

This antibody has weak cross-reactivity with p38 gamma/mapk12.

Host

Rabbit

Positive Control

A431 cell lysate, Caco-2 cell lysate.

Conjugation

Unconjugated

Clonality

Polyclonal

APPLICATION DILUTION

  • WB

  • 1:5,000

PROPERTIES

Form

Liquid

Storage Condition

Shipped at 4C. Store at +4C short term (1-2 weeks). It is recommended to aliquot into single-use upon delivery. Store at -20C long term.

Storage Buffer

1*PBS (pH7.4), 0.1% BSA, 40% Glycerol, 0.2% Proclean 950.

Concentration

2ug/ul

Purification

Immunogen affinity purified.

Molecular Weight

Predicted band size: 42 kDa

Isotype

IgG

TARGET

UNIPROT #

O15264

PROTEIN NAME

p38 delta / MAPK13

SYNONYMS

Mitogen-activated protein kinase 13;EC:2.7.11.24;MAP kinase 13;MAPK 13;Mitogen-activated protein kinase p38 delta;MAP kinase p38 delta;Stress-activated protein kinase 4;MAPK13;PRKM13;SAPK4

SUBCELLULAR LOCATION

Cytoplasm, cytosol, nucleus.

FUNCTION

Mitogen-activated protein kinase 13 (MAPK 13), also known as stress-activated protein kinase 4 (SAPK4), is an enzyme that in humans is encoded by the MAPK13 gene. The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is closely related to p38 MAP kinase, both of which can be activated by proinflammatory cytokines and cellular stress. MAP kinase kinases 3, and 6 can phosphorylate and activate this kinase. Transcription factor ATF2, and microtubule dynamics regulator stathmin have been shown to be the substrates of this kinase.

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