NLRX1 Rabbit Polyclonal Antibody (HA500621)

UNIPROT #

Q86UT6

PROTEIN NAME

NLRX1

SYNONYMS

Caterpiller protein 11.3 antibody;CLR11.3 antibody;DLNB26 antibody;FLJ21478 antibody;MGC131937 antibody;MGC21025 antibody;NLR family member X1 antibody;NLR family;X1 antibody;Nlrx1 antibody;NLRX1_HUMAN antibody;NOD-like receptor X1 antibody;NOD26 antibody;NOD5 antibody;NOD9 antibody;Nucleotide-binding oligomerization domain protein 26 antibody;Nucleotide-binding oligomerization domain protein 5 antibody;Nucleotide-binding oligomerization domain protein 9 antibody;nucleotide-binding oligomerization domain leucine rich repeat containing X1 antibody;Protein Caterpiller 11.3 antibody

SUBCELLULAR LOCATION

Mitochondrion outer membrane.

FUNCTION

NLRX1 or NLR family member X1, short for nucleotide-binding oligomerization domain, leucine rich repeat containing X1 is a protein that in humans is encoded by the NLRX1 gene. It is also known as NOD-like receptor X1, NLR family, X1, NOD5, NOD9, and CLR11.3, and is a member of the NOD-like receptor family of pattern recognition receptors. NLRX1 is an intracellular protein that plays a role in the immune system. NLRX1 also plays a role in host immunity during bacterial infections, such as Chlamydia trachomatis and Helicobacter pylori, by regulating bacterial burden and inflammation in mononuclear phagocytes. Mechanisms underlying the modulation of NLRX1 are not well characterized, however computational modeling predictions suggest that levels of NLRX1 may be controlled by negative feedback circuits induced early after infection.