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NeuN Recombinant Antibody [SR45-07] - Rat IgG1 (Chimeric) - BSA and Azide free (HA610237)

Price: Regular price $649.00

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Catalog# HA610237

to NeuN

Tested for

  • IHC-Fr

  • IHC-P

Reacts with

  • Human

  • Mouse

  • Rat

  • Cynomolgus monkey

  • Pig

Recombinant production enables lot-to-lot consistency and is animal-cruelty-free

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Specifications

Product Type

Recombinant Chimeric Antibody primary

Product Name

NeuN Recombinant Antibody [SR45-07] - Rat IgG1 (Chimeric) - BSA and Azide free (HA610237)

Immunogen

Synthetic peptide within human neun aa 20-60.

Positive Control

Human cerebellum tissue, mouse cerebellum tissue, rat cerebellum tissue.

Conjugation

Unconjugated

Clone Number

SR45-07

APPLICATION DILUTION

  • IHC-Fr

  • 1:1,000

  • IHC-P

  • 1:2,000

PROPERTIES

Form

Liquid

Storage Condition

Store at +4C after thawing. Aliquot store at -20C. Avoid repeated freeze / thaw cycles.

Storage Buffer

1*PBS (pH7.4).

Concentration

1ug/ul

Purification

Protein A affinity purified.

Molecular Weight

Predicted band size: 34 kDa

TARGET

UNIPROT #

A6NFN3

PROTEIN NAME

NeuN

SYNONYMS

FLJ56884 antibody;FLJ58356 antibody;Fox-1 homolog C antibody;fox1 homolog C antibody;Fox3 antibody;FOX3NeuN antibody;hexaribonucleotide binding protein 3 antibody;HRNBP3 antibody;NEUN antibody;neuronal nuclei antibody;Rbfox3 antibody;RFOX3_HUMAN antibody;RNA binding protein fox-1 homolog 3 antibody;RNA binding protein, fox 1 homolog (C. elegans) 3 antibody

SUBCELLULAR LOCATION

Nucleus, Cytoplasm.

FUNCTION

Neuronal nuclei (NeuN, Fox-3, RBFOX3) is a nuclear protein expressed in most post-mitotic neurons of the central and peripheral nervous systems. NeuN is not detected in Purkinje cells, sympathetic ganglion cells, Cajal-Retzius cells, INL retinal cells, inferior olivary, and dentate nucleus neurons. This neuronal protein was originally identified by immunoreactivity with a monoclonal antibody also called NeuN. Using MS-analysis, NeuN was later identified as the Fox-3 gene product. Fox-3 contains an RNA recognition motif and functions as a splicing regulator. Fox-3 regulates alternative splicing of NumB, promoting neuronal differentiation during development.

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