NCAM1 / CD56 Recombinant Rabbit Monoclonal Antibody (IRS026)

UNIPROT #

P13591

PROTEIN NAME

NCAM1 / CD56

SYNONYMS

antigen MSK39 identified by monoclonal antibody;5.1H11 antibody;antigen recognized by monoclonal antibody;5.1H11 antibody;CD56 antibody;cell adhesion molecule, neural, 1 antibody;MSK 39 antibody;MSK39 antibody;N-CAM-1 antibody;NCAM 1 antibody;NCAM antibody;NCAM C antibody;NCAM-1 antibody;NCAM1 antibody;NCAM1_HUMAN antibody;NCAMC antibody;Neural cell adhesion molecule 1 antibody;Neural cell adhesion molecule NCAM antibody;OTTHUMP00000235666 antibody

SUBCELLULAR LOCATION

Cell membrane, Secreted.

FUNCTION

Neural cell adhesion molecules (NCAMs) are a family of closely related cell surface glycoproteins involved in cell to cell interactions during growth and thought to play an important role in embryogenesis and development. The expression of these molecules is widespread in all three germ layers during embryogenesis, but is more restrictive in adult tissues. NCAM expression is observed in a variety of human tumors including neuroblastomas, rhabdo-myosarcomas, Wilms' tumor, Ewing's sarcoma and some primitive myeloid malignancies. Multiple isoforms of NCAM have been reported in both mouse and human brain tissue. In humans, NCAMs arise from differential splicing and use of alternative polyadenylation sites of a single gene mapping to 11q23.