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MUC2 Recombinant Rabbit Monoclonal Antibody (IRS235RB)

Price: Regular price $278.00

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Catalog# IRS235RB

Rabbit Monoclonal to MUC2

Tested for

  • mIHC

Reacts with

  • Mouse

Recombinant production enables lot-to-lot consistency and is animal-cruelty-free

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Specifications

Product Type

Recombinant Rabbit monoclonal primary

Product Name

MUC2 Recombinant Rabbit Monoclonal Antibody (IRS235RB)

Immunogen

Synthetic peptide within human muc2 aa 5100-5149 / 5179.

Host

Rabbit

Positive Control

Mouse intestine tissue.

Conjugation

Unconjugated

Clonality

Monoclonal

APPLICATION DILUTION

  • mIHC

  • 1:100

PROPERTIES

Form

Liquid

Storage Condition

Shipped at 4C. Store at +4C short term (1-2 weeks). It is recommended to aliquot into single-use upon delivery. Store at -20C long term.

Storage Buffer

1*PBS (pH7.4), 0.1% BSA, 40% Glycerol, 0.2% Proclean 950.

Purification

Protein A affinity purified.

Molecular Weight

Predicted band size: 551 kDa

Isotype

IgG

TARGET

UNIPROT #

Q80Z19

PROTEIN NAME

MUC2

SYNONYMS

Intestinal mucin 2 antibody;Intestinal mucin-2 antibody;MLP antibody;MUC 2 antibody;MUC-2 antibody;Muc2 antibody;MUC2_HUMAN antibody;Mucin 2 antibody;Mucin 2 intestinal antibody;Mucin 2 intestinal/tracheal antibody;Mucin 2 oligomeric mucus/gel forming antibody;Mucin 2 precursor antibody;Mucin 2 tracheal antibody;Mucin like protein antibody;Mucin-2 antibody;Mucin2 antibody;SMUC antibody

SUBCELLULAR LOCATION

Secreted.

FUNCTION

The mucins are a family of highly glycosylated, secreted proteins with a basic structure consisting of a variable number of tandem repeats (VNTRs) encoded by 60 base pairs (Mucin 1), 69 base pairs (Mucin 2) and 51 base pairs (Mucin 3). The number of repeats is highly polymorphic and varies among different alleles. Mucin 1 proteins are expressed as type I membrane proteins in addition to secreted forms. Mucin 1 is aberrantly expressed in epithelial tumors including breast carcinomas. Mucin 2 coats the epithelia of the intestines and airways and is associated with colonic tumors. Mucin 3 is a major com-ponent of various mucus gels and is broadly expressed in normal and tumor cells.

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