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Mouse Von Willebrand Factor/vWF Protein (HA211245)

Price: Regular price $159.00

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Catalog# HA211245

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  • Mouse

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Product Details

Product Type

Protein

Product Name

Mouse Von Willebrand Factor/vWF Protein (HA211245)

Predicted molecular mass

146 kD

Protein construction description

A DNA sequence encoding the mouse Von Willebrand Factor/vWF (Q8CIZ8-1) (Asp 1498-Lys 2813) was expressed with a His tag at the C-terminus.

Accession

Q8CIZ8-1

Protein construction

Von Willebrand Factor/vWF (1498-2813) | His

Source

HEK293

Bio Activity

Testing in progress.

Purity

>95% as determined by SDS-PAGE.

Endotoxin

Less than 1.0 EU per μg by the LAL method.

Formulation

Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4, 5% Trehalose, 5% mannitol.

Species

Mouse

Background

Von Willebrand factor (VWF) is a blood glycoprotein that promotes hemostasis, specifically, platelet adhesion. It is deficient and/or defective in von Willebrand disease and is involved in many other diseases, including thrombotic thrombocytopenic purpura, Heyde's syndrome, and possibly hemolytic–uremic syndrome. Increased plasma levels in many cardiovascular, neoplastic, metabolic (e.g. diabetes), and connective tissue diseases are presumed to arise from adverse changes to the endothelium, and may predict an increased risk of thrombosis.

Usage Guide

Shipping

In general, recombinant proteins are provided as lyophilized powder which are shipped with blue ice. Bulk packages of recombinant proteins are provided as frozen liquid which are shipped with dry ice.

Storage

Please avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃ It is recommended that aliquot the reconstituted solution to minimize freeze-thaw cycles.

Reconstitution

Reconstitute at 250 μg/ml in sterile water.

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