Skip to content

Contact

(857) 353-6600

orders@huabio.com

Mouse Complement C3, C-His Tag Protein (HA211093)

Price: Regular price $800.00

Unit price per 

Product size

Bulk Order Quote   |   Customization Request

Catalog# HA211093

Reacts with

  • Mouse

Safety datasheet

Select your chosen country/region

COA DOWNLOAD

Product Details

Product Type

Protein

Product Name

Mouse Complement C3, C-His Tag Protein (HA211093)

Predicted molecular mass

186 kD

Protein construction description

A DNA sequence encoding the mouse Complement C3 protein (P01027-1) (Ile 25-Asn 1663) was expressed with a His tag at the C-terminus.

Accession

P01027-1

Protein construction

Complement C3 (25-1663) | His

Source

HEK293

Purity

>90% as determined by SDS-PAGE.

Endotoxin

Less than 1.0 EU per μg by the LAL method.

Formulation

Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4, 5% Trehalose, 5% mannitol.

Species

Mouse

Background

C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates. Derived from proteolytic degradation of complement C3, C3a anaphylatoxin is a mediator of local inflammatory process. In chronic inflammation, acts as a chemoattractant for neutrophils (By similarity). It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes. The short isoform has B-cell stimulatory activity.

Usage Guide

Shipping

In general, recombinant proteins are provided as lyophilized powder which are shipped with blue ice. Bulk packages of recombinant proteins are provided as frozen liquid which are shipped with dry ice.

Storage

Please avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -20C to -80C It is recommended that aliquot the reconstituted solution to minimize freeze-thaw cycles.

Reconstitution

Reconstitute at 250 μg/ml in sterile water.

Close (esc)

Popup

Use this popup to embed a mailing list sign up form. Alternatively use it as a simple call to action with a link to a product or a page.

Age verification

By clicking enter you are verifying that you are old enough to consume alcohol.

Enter

Search

Main menu

Your cart is currently empty.
Shop now