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Mouse CD200, C-His Tag Protein (HA211380)

Price: Regular price $129.00

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Catalog# HA211380

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  • Mouse

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Product Details

Product Type

Protein

Product Name

Mouse CD200, C-His Tag Protein (HA211380)

Predicted molecular mass

24.3 kD

Protein construction description

A DNA sequence encoding the mouse CD200 protein (O54901) (Gln 31-Gly 232) was expressed with a His tag at the C-terminus.

Accession

O54901

Protein construction

CD200 (31-232) | His

Source

HEK293

Bio Activity

Testing in progress.

Purity

>95% as determined by SDS-PAGE.

Endotoxin

Less than 1.0 EU per μg by the LAL method.

Formulation

Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4, 5% Trehalose, 5% mannitol.

Species

Mouse

Background

OX-2 membrane glycoprotein, also named CD200 (Cluster of Differentiation 200) is a human protein encoded by the CD200 gene. In mice, the CD200 gene is located on chromosome 16. CD200 is expressed on dendritic cells, activated B lymphocytes, activated T lymphocytes, thymocytes, endothelial cells, neurons and osteoblast precursors. In innate immunity, cellular CD200 expression is induced upon TLR and NLR activation. At the transcriptional level, CD200 expression is regulated by C/EBP-β. It has been shown that CD200 expression is induced by IFN-γ and TNF-α in a NF-kappaB-, STAT1- and IRF-1-dependent manner.

Usage Guide

Shipping

In general, recombinant proteins are provided as lyophilized powder which are shipped with blue ice. Bulk packages of recombinant proteins are provided as frozen liquid which are shipped with dry ice.

Storage

Please avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃ It is recommended that aliquot the reconstituted solution to minimize freeze-thaw cycles.

Reconstitution

Reconstitute at 250 μg/ml in sterile water.

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