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LDHA Recombinant Rabbit Monoclonal Antibody - BSA and Azide free [PSH13-58] (HA751477)

Price: Regular price $649.00

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Catalog# HA751477

Rabbit Monoclonal to LDHA

Tested for

  • WB

  • IHC-P

  • IF-Cell

  • FC

Reacts with

  • Human

  • Mouse

  • Rat

Recombinant production enables lot-to-lot consistency and is animal-cruelty-free

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Specifications

Product Type

Recombinant Rabbit monoclonal primary

Product Name

LDHA Recombinant Rabbit Monoclonal Antibody - BSA and Azide free [PSH13-58] (HA751477)

Immunogen

Synthetic peptide within human ldha aa 1-50 / 332.

Host

Rabbit

Positive Control

HepG2 cell lysate, HeLa cell lysate, MCF7 cell lysate, A431 cell lysate, 293T cell lysate, PANC-1 cell lysate, U-87 MG cell lysate, MDA-MB-231 cell lysate, NIH/3T3 cell lysate, RAW264.7 cell lysate, Neuro-2a cell lysate, C2C12 cell lysate, C6 cell lysate, PC-12 cell lysate, human breast cancer tissue, human liver tissue, mouse heart tissue, mouse liver tissue, rat liver tissue, HeLa, C2C12, PC-12.

Conjugation

Unconjugated

Clonality

Monoclonal

Clone Number

PSH13-58

APPLICATION DILUTION

  • WB

  • 1:5,000-1:10,000

  • IHC-P

  • 1:5,000-1:20,000

  • IF-Cell

  • 1:500

  • FC

  • 1:1,000

PROPERTIES

Form

Liquid

Storage Condition

Store at +4C after thawing. Aliquot store at -20C. Avoid repeated freeze / thaw cycles.

Storage Buffer

1*PBS (pH7.4).

Concentration

1ug/ul

Purification

Protein A affinity purified.

Molecular Weight

Predicted band size: 37 kDa

Isotype

IgG

TARGET

UNIPROT #

P00338

PROTEIN NAME

LDHA

SYNONYMS

Cell proliferation-inducing gene 19 protein antibody;L-lactate dehydrogenase A chain antibody;LDH muscle subunit antibody;LDH-A antibody;LDH-M antibody;ldha antibody;LDHA_HUMAN antibody;Renal carcinoma antigen NY-REN-59 antibody

SUBCELLULAR LOCATION

Cytoplasm.

FUNCTION

Lactate dehydrogenase A (LDHA) is an enzyme which in humans is encoded by the LDHA gene. It is a monomer of lactate dehydrogenase, which exists as a tetramer. The other main subunit is lactate dehydrogenase B (LDHB). Lactate dehydrogenase A catalyzes the inter-conversion of pyruvate and L-lactate with concomitant inter-conversion of NADH and NAD+. LDHA is found in most somatic tissues, though predominantly in muscle tissue and tumors, and belongs to the lactate dehydrogenase family. It has long been known that many human cancers have higher LDHA levels compared to normal tissues. It has also been shown that LDHA plays an important role in the development, invasion and metastasis of malignancies. Mutations in LDHA have been linked to exertional myoglobinuria.

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