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ICAM3 Recombinant Rabbit Monoclonal Antibody [PSH20-97] (HA724192)

Price: Regular price $385.00

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Catalog# HA724192

Rabbit Monoclonal to ICAM3

Tested for

  • WB

  • IF-Cell

  • IHC-P

  • FC

  • IP

Reacts with

  • Human

Recombinant production enables lot-to-lot consistency and is animal-cruelty-free

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Specifications

Product Type

Recombinant Rabbit monoclonal primary

Product Name

ICAM3 Recombinant Rabbit Monoclonal Antibody [PSH20-97] (HA724192)

Immunogen

Recombinant protein within human icam3 aa 1-485.

Host

Rabbit

Positive Control

U-937 (Human acute monocytic leukemia cells) cell lysate, Jurkat (Human T-lymphoblastic cells) cell lysate, Ramos (Human Burkitt's lymphoma cells) cell lysate, THP-1 (Human acute monoblastic leukemia cells) cell lysate, HL-60 (Human acute promyelocytic leukemia cells) cell lysate.

Conjugation

Unconjugated

Clonality

Monoclonal

Clone Number

PSH20-97

APPLICATION DILUTION

  • WB

  • 1:5,000

  • IF-Cell

  • 1:500

  • IHC-P

  • 1:1,000

  • FC

  • 1:1,000

  • IP

  • 1-2μg/sample

PROPERTIES

Form

Liquid

Storage Condition

Shipped at 4℃. Store at +4℃ short term (1-2 weeks). It is recommended to aliquot into single-use upon delivery. Store at -20℃ long term.

Storage Buffer

1*PBS (pH7.4), 0.1% BSA, 40% Glycerol, 0.2% Proclean 950.

Concentration

1ug/ul

Purification

Protein A affinity purified.

Molecular Weight

Predicted band size: 60 kDa

Isotype

IgG

TARGET

UNIPROT #

P32942

PROTEIN NAME

ICAM3

SYNONYMS

CD50 antibody;CDW 50 antibody;CDw50 antibody;ICAM 3 antibody;ICAM-3 antibody;ICAM-R antibody;ICAM3 antibody;ICAM3_HUMAN antibody;ICAMR antibody;Intercellular adhesion molecule 3 antibody

SUBCELLULAR LOCATION

Membrane.

FUNCTION

Intercellular adhesion molecule 3 (ICAM3) also known as CD50 (Cluster of Differentiation 50), is a protein that in humans is encoded by the ICAM3 gene. The protein is constitutively expressed on the surface of leukocytes, which are also called white blood cells and are part of the immune system. ICAM3 mediates adhesion between cells by binding to specific integrin receptors. It plays an important role in the immune cell response through its facilitation of interactions between T cells and dendritic cells, which allows for T cell activation. ICAM3 also mediates the clearance of cells undergoing apoptosis by attracting and binding macrophages, a type of cell that breaks down infected or dying cells through a process known as phagocytosis, to apoptotic cells.

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