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Human ULBP1/NKG2DL1, C-His Tag Protein (HA210963)

Price: Regular price $379.00

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Catalog# HA210963

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  • Human

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Product Details

Product Type

Protein

Product Name

Human ULBP1/NKG2DL1, C-His Tag Protein (HA210963)

Predicted molecular mass

23.7 kD

Protein construction description

A DNA sequence encoding the human ULBP1/NKG2DL1 protein (Q9BZM6) (Gly 26-Gly 216) was expressed with a His tag at the C-terminus.

Accession

Q9BZM6

Protein construction

ULBP1/NKG2DL1 (26-216) | His

Source

HEK293

Bio Activity

Testing in progress.

Purity

>95% as determined by SDS-PAGE.

Endotoxin

Less than 1.0 EU per μg by the LAL method.

Formulation

Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4, 5% Trehalose, 5% mannitol.

Species

Human

Background

The protein encoded by this gene is a ligand of natural killer group 2, member D (NKG2D), an immune system-activating receptor on NK cells and T-cells. Binding of the encoded ligand to NKG2D leads to activation of several signal transduction pathways, including those of JAK2, STAT5, ERK and PI3K kinase/Akt. Also, in cytomegalovirus-infected cells, this ligand binds the UL16 glycoprotein and is prevented from activating the immune system. Three transcript variants encoding different isoforms have been found for this gene.

Usage Guide

Shipping

In general, recombinant proteins are provided as lyophilized powder which are shipped with blue ice. Bulk packages of recombinant proteins are provided as frozen liquid which are shipped with dry ice.

Storage

Please avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -20C to -80C It is recommended that aliquot the reconstituted solution to minimize freeze-thaw cycles.

Reconstitution

Reconstitute at 250 μg/ml in sterile water.

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