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Human SOST/Sclerostin, Tag Free Protein (HA211397)

Price: Regular price $129.00

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Catalog# HA211397

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  • Human

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Product Details

Product Type

Protein

Product Name

Human SOST/Sclerostin, Tag Free Protein (HA211397)

Predicted molecular mass

22.3 kD

Protein construction description

A DNA sequence encoding the human SOST/Sclerostin protein (Q9BQB4-1) (Gln 24-Tyr 213) was expressed with tag Free.

Accession

Q9BQB4-1

Protein construction

SOST/Sclerostin (24-213)

Source

HEK293

Bio Activity

Testing in progress.

Purity

>95% as determined by SDS-PAGE.

Endotoxin

Less than 1.0 EU per μg by the LAL method.

Formulation

Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4, 5% Trehalose, 5% mannitol.

Species

Human

Background

Sclerostin is a protein that in humans is encoded by the SOST gene. It is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Sclerostin is produced primarily by the osteocyte but is also expressed in other tissues, and has anti-anabolic effects on bone formation.

Usage Guide

Shipping

In general, recombinant proteins are provided as lyophilized powder which are shipped with blue ice. Bulk packages of recombinant proteins are provided as frozen liquid which are shipped with dry ice.

Storage

Please avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃ It is recommended that aliquot the reconstituted solution to minimize freeze-thaw cycles.

Reconstitution

Reconstitute at 250 μg/ml in sterile water.

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