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Human RANK/TNFRSF11A, C-His Tag Protein (HA211522)

Price: Regular price $129.00

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Catalog# HA211522

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  • Human

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Product Details

Product Type

Protein

Product Name

Human RANK/TNFRSF11A, C-His Tag Protein (HA211522)

Predicted molecular mass

21.5 kD

Protein construction description

A DNA sequence encoding the human RANK/TNFRSF11A protein (Q9Y6Q6-1) (Ile 30-Pro 212) was expressed with a His tag at the C-terminus.

Accession

Q9Y6Q6-1

Protein construction

RANK/TNFRSF11A (30-212) | His

Source

HEK293

Bio Activity

Testing in progress.

Purity

>95% as determined by SDS-PAGE.

Endotoxin

Less than 1.0 EU per μg by the LAL method.

Formulation

Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4, 5% Trehalose, 5% mannitol.

Species

Human

Background

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptors can interact with various TRAF family proteins, through which this receptor induces the activation of NF-kappa B and MAPK8/JNK. This receptor and its ligand are important regulators of the interaction between T cells and dendritic cells. This receptor is also an essential mediator for osteoclast and lymph node development. Mutations at this locus have been associated with familial expansile osteolysis, autosomal recessive osteopetrosis, and Paget disease of bone. Alternatively spliced transcript variants have been described for this locus.

Usage Guide

Shipping

In general, recombinant proteins are provided as lyophilized powder which are shipped with blue ice. Bulk packages of recombinant proteins are provided as frozen liquid which are shipped with dry ice.

Storage

Please avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃ It is recommended that aliquot the reconstituted solution to minimize freeze-thaw cycles.

Reconstitution

Reconstitute at 250 μg/ml in sterile water.

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