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Human Osteoactivin/GPNMB, C-His Tag (ECD) Protein (HA210623)

Price: Regular price $389.00

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Catalog# HA210623

Reacts with

  • Human

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Product Details

Product Type

Protein

Product Name

Human Osteoactivin/GPNMB, C-His Tag (ECD) Protein (HA210623)

Predicted molecular mass

53.4 kD

Protein construction description

A DNA sequence encoding the human Osteoactivin/GPNMB protein (Q14956) (Ala 22-Pro 486) was expressed with a His tag at the C-terminus.

Accession

Q14956

Protein construction

Osteoactivin/GPNMB (22-486) | His

Source

HEK293

Bio Activity

Testing in progress.

Purity

>95% as determined by SDS-PAGE.

Endotoxin

Less than 1.0 EU per μg by the LAL method.

Formulation

Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4, 5% Trehalose, 5% mannitol.

Species

Human

Background

The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene.

Usage Guide

Shipping

In general, recombinant proteins are provided as lyophilized powder which are shipped with blue ice. Bulk packages of recombinant proteins are provided as frozen liquid which are shipped with dry ice.

Storage

Please avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -20C to -80C It is recommended that aliquot the reconstituted solution to minimize freeze-thaw cycles.

Reconstitution

Reconstitute at 250 μg/ml in sterile water.

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