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Human MMP8/CLG1, C-His, Flag Tag Protein (HA210646)

Price: Regular price $389.00

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Catalog# HA210646

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  • Human

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Product Details

Product Type

Protein

Product Name

Human MMP8/CLG1, C-His, Flag Tag Protein (HA210646)

Predicted molecular mass

53.8 kD

Protein construction description

A DNA sequence encoding the human MMP8/CLG1 protein (P22894) (Phe 21-Gly 467) was expressed with a Flag tag at the C-terminus.

Accession

P22894

Protein construction

MMP8/CLG1 (21-467) | His | Flag

Source

HEK293

Bio Activity

Testing in progress.

Purity

>95% as determined by SDS-PAGE.

Endotoxin

Less than 1.0 EU per μg by the LAL method.

Formulation

Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4, 5% Trehalose, 5% mannitol.

Species

Human

Background

This gene encodes a member of the matrix metalloproteinase (MMP) family of proteins. These proteins are involved in the breakdown of extracellular matrix in embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Proteolysis at different sites on this protein results in multiple active forms of the enzyme with distinct N-termini. This protein functions in the degradation of type I, II and III collagens. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. Alternative splicing results in multiple transcript variants.

Usage Guide

Shipping

In general, recombinant proteins are provided as lyophilized powder which are shipped with blue ice. Bulk packages of recombinant proteins are provided as frozen liquid which are shipped with dry ice.

Storage

Please avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -20C to -80C It is recommended that aliquot the reconstituted solution to minimize freeze-thaw cycles.

Reconstitution

Reconstitute at 250 μg/ml in sterile water.

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