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Human IL-36 gamma/IL-1 F9, Tag Free Protein (HA211355)

Price: Regular price $129.00

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Catalog# HA211355

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  • Human

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Product Details

Product Type

Protein

Product Name

Human IL-36 gamma/IL-1 F9, Tag Free Protein (HA211355)

Predicted molecular mass

17.8 kD

Protein construction description

A DNA sequence encoding the human IL-36 gamma/IL-1 F9 protein (Q9NZH8-1) (Ser 18-Asp 169) was expressed with tag free.

Accession

Q9NZH8-1

Protein construction

IL-36 gamma/IL-1 F9 (18-169)

Source

HEK293

Bio Activity

Testing in progress.

Endotoxin

Less than 1.0 EU per μg by the LAL method.

Formulation

Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4, 5% Trehalose, 5% mannitol.

Species

Human

Background

The protein encoded by this gene is a member of the interleukin 1 cytokine family. The activity of this cytokine is mediated by interleukin 1 receptor-like 2 (IL1RL2/IL1R-rp2), and is specifically inhibited by interleukin 1 family, member 5 (IL1F5/IL-1 delta). Interferon-gamma, tumor necrosis factor-alpha and interleukin 1, beta (IL1B) are reported to stimulate the expression of this cytokine in keratinocytes. The expression of this cytokine in keratinocytes can also be induced by a contact hypersensitivity reaction or herpes simplex virus infection. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Usage Guide

Shipping

In general, recombinant proteins are provided as lyophilized powder which are shipped with blue ice. Bulk packages of recombinant proteins are provided as frozen liquid which are shipped with dry ice.

Storage

Please avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -20C to -80C It is recommended that aliquot the reconstituted solution to minimize freeze-thaw cycles.

Reconstitution

Reconstitute at 250 μg/ml in sterile water.

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