Skip to content

Contact

(857) 353-6600

orders@huabio.com

Human IL-21, C-His, Flag Tag Protein (HA210578)

Price: Regular price $389.00

Unit price per 

Product size

Bulk Order Quote   |   Customization Request

Catalog# HA210578

Reacts with

  • Human

Safety datasheet

Select your chosen country/region

COA DOWNLOAD

Product Details

Product Type

Protein

Product Name

Human IL-21, C-His, Flag Tag Protein (HA210578)

Predicted molecular mass

18 kD

Protein construction description

A DNA sequence encoding the human IL-21 protein (Q9HBE4) (Gln 32-Ser 162) was expressed with both His, Flag tag at the C-terminus.

Accession

Q9HBE4

Protein construction

IL-21 (32-162) | His | Flag

Source

HEK293

Bio Activity

Testing in progress.

Purity

>90% as determined by SDS-PAGE.

Endotoxin

Less than 1.0 EU per μg by the LAL method.

Formulation

Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4, 5% Trehalose, 5% mannitol.

Species

Human

Background

Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG1 and IgG3 in B-cells. Implicated in the generation and maintenance of T follicular helper (Tfh) cells and the formation of germinal-centers. Together with IL6, control the early generation of Tfh cells and are critical for an effective antibody response to acute viral infection. May play a role in proliferation and maturation of natural killer (NK) cells in synergy with IL15. May regulate proliferation of mature B- and T-cells in response to activating stimuli. In synergy with IL15 and IL18 stimulates interferon gamma production in T-cells and NK cells. During T-cell mediated immune response may inhibit dendritic cells (DC) activation and maturation.

Usage Guide

Shipping

In general, recombinant proteins are provided as lyophilized powder which are shipped with blue ice. Bulk packages of recombinant proteins are provided as frozen liquid which are shipped with dry ice.

Storage

Please avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -20C to -80C It is recommended that aliquot the reconstituted solution to minimize freeze-thaw cycles.

Reconstitution

Reconstitute at 250 μg/ml in sterile water.

Close (esc)

Popup

Use this popup to embed a mailing list sign up form. Alternatively use it as a simple call to action with a link to a product or a page.

Age verification

By clicking enter you are verifying that you are old enough to consume alcohol.

Enter

Search

Main menu

Your cart is currently empty.
Shop now