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Human GDF-15, Tag Free Protein (HA211526)

Price: Regular price $169.00

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Catalog# HA211526

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  • Human

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Product Details

Product Type

Protein

Product Name

Human GDF-15, Tag Free Protein (HA211526)

Predicted molecular mass

12.7 kD

Protein construction description

A DNA sequence encoding the human GDF-15 protein (Q99988) (Ala 195-Ser 308) was expressed with tag Free.

Accession

Q99988

Protein construction

GDF-15 (195-308)

Source

HEK293

Bio Activity

Testing in progress.

Purity

>95% as determined by SDS-PAGE.

Endotoxin

Less than 1.0 EU per μg by the LAL method.

Formulation

100mM HAC, pH 2.9, 5% trehalose, 5% mannitol

Species

Human

Background

Growth/differentiation factor 15 is a protein that in humans is encoded by the GDF15 gene. GDF15 was first identified as Macrophage inhibitory cytokine-1 or MIC-1. It is a protein belonging to the transforming growth factor beta superfamily. Under normal conditions, GDF15 is expressed in low concentrations in most organs and upregulated because of injury of organs such as liver, kidney, heart and lung. The function of GDF15 is not fully clear but it seems to have a role in regulating inflammatory pathways and to be involved in regulating apoptosis, angiogenesis, cell repair and cell growth, which are biological processes observed in cardiovascular and neoplastic disorders.

Usage Guide

Shipping

In general, recombinant proteins are provided as lyophilized powder which are shipped with blue ice. Bulk packages of recombinant proteins are provided as frozen liquid which are shipped with dry ice.

Storage

Please avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃ It is recommended that aliquot the reconstituted solution to minimize freeze-thaw cycles.

Reconstitution

Reconstitute at 250 μg/ml in 4mM HCL buffer.

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