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Human Fibromodulin/FMOD, Tag Free Protein (HA211358)

Price: Regular price $129.00

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Catalog# HA211358

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  • Human

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Product Details

Product Type

Protein

Product Name

Human Fibromodulin/FMOD, Tag Free Protein (HA211358)

Predicted molecular mass

41.6 kD

Protein construction description

A DNA sequence encoding the human Fibromodulin/FMOD protein (Q06828) (Gln 19-Ile 376) was expressed with tag free.

Accession

Q06828

Protein construction

Fibromodulin/FMOD (19-376)

Source

HEK293

Bio Activity

Testing in progress.

Purity

>95% as determined by SDS-PAGE.

Endotoxin

Less than 1.0 EU per μg by the LAL method.

Formulation

Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4, 5% Trehalose, 5% mannitol.

Species

Human

Background

Affects the rate of fibrils formation. May have a primary role in collagen fibrillogenesis (By similarity). Fibromodulin belongs to the family of small interstitial proteoglycans. The encoded protein possesses a central region containing leucine-rich repeats with 4 keratan sulfate chains, flanked by terminal domains containing disulphide bonds. Owing to the interaction with type I and type II collagen fibrils and in vitro inhibition of fibrillogenesis, the encoded protein may play a role in the assembly of extracellular matrix. It may also regulate TGF-beta activities by sequestering TGF-beta into the extracellular matrix. Sequence variations in this gene may be associated with the pathogenesis of high myopia. Alternative splicing results in multiple transcript variants.

Usage Guide

Shipping

In general, recombinant proteins are provided as lyophilized powder which are shipped with blue ice. Bulk packages of recombinant proteins are provided as frozen liquid which are shipped with dry ice.

Storage

Please avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃ It is recommended that aliquot the reconstituted solution to minimize freeze-thaw cycles.

Reconstitution

Reconstitute at 250 μg/ml in sterile water.

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