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Human E-Cadherin, C-His Tag (ECD) Protein (HA210886)

Price: Regular price $389.00

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Catalog# HA210886

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  • Human

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Product Details

Product Type

Protein

Product Name

Human E-Cadherin, C-His Tag (ECD) Protein (HA210886)

Predicted molecular mass

61.7 kD

Protein construction description

A DNA sequence encoding the human E-Cadherin protein (P12830-1) (Asp 155-Ile 707) was expressed with a His tag at the C-terminus.

Accession

P12830-1

Protein construction

E-Cadherin (155-707) | His

Source

HEK293

Bio Activity

Testing in progress.

Purity

>95% as determined by SDS-PAGE.

Endotoxin

Less than 1.0 EU per μg by the LAL method.

Formulation

Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4, 5% Trehalose, 5% mannitol.

Species

Human

Background

Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. E-Cad/CTF2 promotes non-amyloidogenic degradation of Abeta precursors. Has a strong inhibitory effect on APP C99 and C83 production.

Usage Guide

Shipping

In general, recombinant proteins are provided as lyophilized powder which are shipped with blue ice. Bulk packages of recombinant proteins are provided as frozen liquid which are shipped with dry ice.

Storage

Please avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -20C to -80C It is recommended that aliquot the reconstituted solution to minimize freeze-thaw cycles.

Reconstitution

Reconstitute at 250 μg/ml in sterile water.

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