Skip to content

Contact

(857) 353-6600

orders@huabio.com

Human Chitinase 3-like 1/CHI3L1, C-His Tag Protein (HA211030)

Price: Regular price $379.00

Unit price per 

Product size

Bulk Order Quote   |   Customization Request

Catalog# HA211030

Reacts with

  • Human

Safety datasheet

Select your chosen country/region

COA DOWNLOAD

Product Details

Product Type

Protein

Product Name

Human Chitinase 3-like 1/CHI3L1, C-His Tag Protein (HA211030)

Predicted molecular mass

41.9 kD

Protein construction description

A DNA sequence encoding the human Chitinase 3-like 1/CHI3L1 protein (P36222) (Tyr 22-Thr 383) was expressed with a His tag at the C-terminus.

Accession

P36222

Protein construction

Chitinase 3-like 1/CHI3L1 (22-383) | His

Source

HEK293

Bio Activity

Testing in progress.

Purity

>95% as determined by SDS-PAGE.

Endotoxin

Less than 1.0 EU per μg by the LAL method.

Formulation

Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4, 5% Trehalose, 5% mannitol.

Species

Human

Background

Carbohydrate-binding lectin with a preference for chitin. Has no chitinase activity. May play a role in tissue remodeling and in the capacity of cells to respond to and cope with changes in their environment. Plays a role in T-helper cell type 2 (Th2) inflammatory response and IL-13-induced inflammation, regulating allergen sensitization, inflammatory cell apoptosis, dendritic cell accumulation and M2 macrophage differentiation. Facilitates invasion of pathogenic enteric bacteria into colonic mucosa and lymphoid organs. Mediates activation of AKT1 signaling pathway and subsequent IL8 production in colonic epithelial cells. Regulates antibacterial responses in lung by contributing to macrophage bacterial killing, controlling bacterial dissemination and augmenting host tolerance. Also regulates hyperoxia-induced injury, inflammation and epithelial apoptosis in lung.

Usage Guide

Shipping

In general, recombinant proteins are provided as lyophilized powder which are shipped with blue ice. Bulk packages of recombinant proteins are provided as frozen liquid which are shipped with dry ice.

Storage

Please avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -20C to -80C It is recommended that aliquot the reconstituted solution to minimize freeze-thaw cycles.

Reconstitution

Reconstitute at 250 μg/ml in sterile water.

Close (esc)

Popup

Use this popup to embed a mailing list sign up form. Alternatively use it as a simple call to action with a link to a product or a page.

Age verification

By clicking enter you are verifying that you are old enough to consume alcohol.

Enter

Search

Main menu

Your cart is currently empty.
Shop now