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Human CDCP1/CD318, N-Twin Strep, C-His, Flag Tag Protein (HA210664)

Price: Regular price $379.00

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Catalog# HA210664

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  • Human

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Product Details

Product Type

Protein

Product Name

Human CDCP1/CD318, N-Twin Strep, C-His, Flag Tag Protein (HA210664)

Predicted molecular mass

23 kD

Protein construction description

A DNA sequence encoding the human CDCP1/CD318 protein (Q9H5V8) (Cys 689-Glu 836) was expressed with a Twin strep tag at the N-terminus and both His, Flag tag at the C-terminus.

Accession

Q9H5V8

Protein construction

Twin Strep | CDCP1/CD318 (689-836) | His | Flag

Source

E.coli

Bio Activity

Testing in progress.

Purity

>95% as determined by SDS-PAGE.

Endotoxin

Less than 1.0 EU per μg by the LAL method.

Formulation

Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4, 5% Trehalose, 5% mannitol.

Species

Human

Background

This gene encodes a transmembrane protein which contains three extracellular CUB domains and acts as a substrate for Src family kinases. The protein plays a role in the tyrosine phosphorylation-dependent regulation of cellular events that are involved in tumor invasion and metastasis. Alternative splicing results in multiple transcript variants of this gene. May be involved in cell adhesion and cell matrix association. May play a role in the regulation of anchorage versus migration or proliferation versus differentiation via its phosphorylation. May be a novel marker for leukemia diagnosis and for immature hematopoietic stem cell subsets. Belongs to the tetraspanin web involved in tumor progression and metastasis.

Usage Guide

Shipping

In general, recombinant proteins are provided as lyophilized powder which are shipped with blue ice. Bulk packages of recombinant proteins are provided as frozen liquid which are shipped with dry ice.

Storage

Please avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -20C to -80C It is recommended that aliquot the reconstituted solution to minimize freeze-thaw cycles.

Reconstitution

Reconstitute at 250 μg/ml in sterile water.

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