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Human C1QA, C-hFc Tag Protein (HA211425)

Price: Regular price $129.00

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Catalog# HA211425

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  • Human

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Product Details

Product Type

Protein

Product Name

Human C1QA, C-hFc Tag Protein (HA211425)

Predicted molecular mass

51.7 kD

Protein construction description

A DNA sequence encoding the human C1QA protein (P02745) (Glu 23-Ala 245) was expressed with a hFc tag at the C-terminus.

Accession

P02745

Protein construction

C1QA (23-245) | hFc

Source

HEK293

Bio Activity

Testing in progress.

Purity

>90% as determined by SDS-PAGE.

Endotoxin

Less than 1.0 EU per μg by the LAL method.

Formulation

Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4, 5% Trehalose, 5% mannitol.

Species

Human

Background

Complement C1q subcomponent subunit A is a protein that in humans is encoded by the C1QA gene. This gene encodes a major constituent of the human complement system subcomponent C1q. C1q associates with C1r and C1s in order to yield the first component of the serum complement system. Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N terminus and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A-C-B on chromosome 1. This gene encodes the A-chain polypeptide of human complement subcomponent C1q.

Usage Guide

Shipping

In general, recombinant proteins are provided as lyophilized powder which are shipped with blue ice. Bulk packages of recombinant proteins are provided as frozen liquid which are shipped with dry ice.

Storage

Please avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃ It is recommended that aliquot the reconstituted solution to minimize freeze-thaw cycles.

Reconstitution

Reconstitute at 250 μg/ml in sterile water.

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