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Human Beta ig-h3/BIGH3/TGFBI, Tag Free Protein (HA211459)

Price: Regular price $129.00

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Catalog# HA211459

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  • Human

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Product Details

Product Type

Protein

Product Name

Human Beta ig-h3/BIGH3/TGFBI, Tag Free Protein (HA211459)

Predicted molecular mass

73.2 kD

Protein construction description

A DNA sequence encoding the human Beta ig-h3/BIGH3/TGFBI protein (Q15582) (Gly 24-His 683) was expressed with tag free.

Accession

Q15582

Protein construction

Beta ig-h3/BIGH3/TGFBI (24-683)

Source

HEK293

Bio Activity

Testing in progress.

Purity

>95% as determined by SDS-PAGE.

Endotoxin

Less than 1.0 EU per μg by the LAL method.

Formulation

Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4, 5% Trehalose, 5% mannitol.

Species

Human

Background

Transforming growth factor, beta-induced, 68kDa, also known as TGFBI (initially called BIGH3, BIG-H3), is a protein which in humans is encoded by the TGFBI gene, locus 5q31. This gene encodes an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. This protein plays a role in cell-collagen interactions and may be involved in endochondrial bone formation in cartilage. The protein is induced by transforming growth factor-beta and acts to inhibit cell adhesion.

Usage Guide

Shipping

In general, recombinant proteins are provided as lyophilized powder which are shipped with blue ice. Bulk packages of recombinant proteins are provided as frozen liquid which are shipped with dry ice.

Storage

Please avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃ It is recommended that aliquot the reconstituted solution to minimize freeze-thaw cycles.

Reconstitution

Reconstitute at 250 μg/ml in sterile water.

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