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Human Arginase 1/ARG1, C-His Tag Protein (HA210914)

Price: Regular price $389.00

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Catalog# HA210914

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  • Human

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Product Details

Product Type

Protein

Product Name

Human Arginase 1/ARG1, C-His Tag Protein (HA210914)

Predicted molecular mass

36.1 kD

Protein construction description

A DNA sequence encoding the human Arginase 1/ARG1 protein (P05089-1) (Met 1-Lys 322) was expressed with a His tag at the C-terminus

Accession

P05089-1

Protein construction

Arginase 1/ARG1 | His

Source

HEK293

Bio Activity

Testing in progress.

Purity

>95% as determined by SDS-PAGE.

Endotoxin

Less than 1.0 EU per μg by the LAL method.

Formulation

Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4, 5% Trehalose, 5% mannitol.

Species

Human

Background

The human ARG1 gene encodes the protein arginase. Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform encoded by this gene, is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia. Two transcript variants encoding different isoforms have been found for this gene.

Usage Guide

Shipping

In general, recombinant proteins are provided as lyophilized powder which are shipped with blue ice. Bulk packages of recombinant proteins are provided as frozen liquid which are shipped with dry ice.

Storage

Please avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -20C to -80C It is recommended that aliquot the reconstituted solution to minimize freeze-thaw cycles.

Reconstitution

Reconstitute at 250 μg/ml in sterile water.

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