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Human Amphiregulin/AREG, C-His Tag Protein (HA211382)

Price: Regular price $119.00

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Catalog# HA211382

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  • Human

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Product Details

Product Type

Protein

Product Name

Human Amphiregulin/AREG, C-His Tag Protein (HA211382)

Predicted molecular mass

20.6 kD

Protein construction description

A DNA sequence encoding the human Amphiregulin/AREG protein (P15514) (Ser 20-Lys 187) was expressed with a His tag at the C-terminus.

Accession

P15514

Protein construction

Amphiregulin/AREG (20-187) | His

Source

HEK293

Bio Activity

Testing in progress.

Purity

>95% as determined by SDS-PAGE.

Endotoxin

Less than 1.0 EU per μg by the LAL method.

Formulation

Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4, 5% Trehalose, 5% mannitol.

Species

Human

Background

Amphiregulin, also known as AREG, is a protein synthesized as a transmembrane glycoprotein with 252 aminoacids and it is encoded by the AREG gene. in humans. The protein encoded by this gene is a member of the epidermal growth factor (EGF) family. It is a critical autocrine growth factor as well as a mitogen for astrocytes, Schwann cells, and fibroblasts. It is a ligand for epidermal growth factor (EGF) and it is related to transforming growth factor alpha (TGF-alpha). This protein interacts with the Epidermal growth factor receptor (EGFR) to promote the growth of normal epithelial cells.

Usage Guide

Shipping

In general, recombinant proteins are provided as lyophilized powder which are shipped with blue ice. Bulk packages of recombinant proteins are provided as frozen liquid which are shipped with dry ice.

Storage

Please avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃ It is recommended that aliquot the reconstituted solution to minimize freeze-thaw cycles.

Reconstitution

Reconstitute at 250 μg/ml in sterile water.

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