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Glucagon Recombinant Rabbit Monoclonal Antibody (IRS150RB)

Price: Regular price $278.00

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Catalog# IRS150RB

Rabbit Monoclonal to Glucagon

Tested for

  • mIHC

Reacts with

  • Human

Recombinant production enables lot-to-lot consistency and is animal-cruelty-free

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Specifications

Product Type

Recombinant Rabbit monoclonal primary

Product Name

Glucagon Recombinant Rabbit Monoclonal Antibody (IRS150RB)

Immunogen

Synthetic peptide within human glucagon aa 40-90.

Host

Rabbit

Positive Control

Rat pancreas tissue, mouse pancreas tissue, human pancreas tissue.

Conjugation

Unconjugated

Clonality

Monoclonal

APPLICATION DILUTION

  • mIHC

  • 1:100

PROPERTIES

Form

Liquid

Storage Condition

Shipped at 4C. Store at +4C short term (1-2 weeks). It is recommended to aliquot into single-use upon delivery. Store at -20C long term.

Storage Buffer

1*PBS (pH7.4), 0.1% BSA, 40% Glycerol, 0.2% Proclean 950.

Purification

Protein A affinity purified.

Molecular Weight

Predicted band size: 21 kDa

Isotype

IgG

TARGET

UNIPROT #

P01275

PROTEIN NAME

Glucagon

SYNONYMS

GCG antibody;glucagon

SUBCELLULAR LOCATION

Secreted.

FUNCTION

Glucagon is a pancreatic hormone that functions as an antagonist to insulin, stimulating the conversion of glycogen to glucose and increasing blood sugar levels. Glucagon-like peptide-1 (GLP-1), Glucagon-like peptide-2 (GLP-2), VIP (vasoactive intestinal peptide) and PACAP (pituitary adenylate cyclase activating polypeptide) are members of the glucagon family of hormones. GLP-1 functions as a transmitter in the central nervous system, inhibiting feeding and drinking behavior, whereas GLP-2 is a stimulator of intestinal epithelial growth. VIP causes vasodilation resulting in the lowering of blood pressure. PACAP is abundant in the hypothalamus and has been shown to increase the synthesis of several hormones, including growth hormone.

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