Gli2 Recombinant Rabbit Monoclonal Antibody - BSA and Azide free [PSH11-23] (HA751402)

UNIPROT #

P10070

PROTEIN NAME

Gli2

SYNONYMS

CJS antibody;Gli 2 antibody;GLI family zinc finger 2 antibody;GLI Kruppel family member GLI2 antibody;GLI2 antibody;GLI2_HUMAN antibody;Glioma associated oncogene family zinc finger antibody;HPE9 antibody;Oncogene GLI2 antibody;PHS2 antibody;Tax helper protein 1 antibody;Tax helper protein 2 antibody;Tax helper protein antibody;Tax responsive element 2 holding protein antibody;Tax responsive element 25 bp sequence binding protein antibody;THP antibody;THP1 antibody;THP2 antibody;Zinc finger protein GLI2 antibody

SUBCELLULAR LOCATION

Nucleus, Cytoplasm, Cell projection, cilium.

FUNCTION

Zinc finger protein GLI2 also known as GLI family zinc finger 2 is a protein that in humans is encoded by the GLI2 gene. The protein encoded by this gene is a transcription factor. GLI2 belongs to the C2H2-type zinc finger protein subclass of the Gli family. Members of this subclass are characterized as transcription factors which bind DNA through zinc finger motifs. These motifs contain conserved H-C links. Gli family zinc finger proteins are mediators of Sonic hedgehog (Shh) signaling and they are implicated as potent oncogenes in the embryonal carcinoma cell. The protein encoded by this gene localizes to the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. It is also thought to play a role during embryogenesis.