FITC Conjugated Human CD10 Recombinant Rabbit Monoclonal Antibody [SN75-07] (HA720209F)

UNIPROT #

P08473

PROTEIN NAME

Human CD10

SYNONYMS

Atriopeptidase antibody;CALLA antibody;CD10 antibody;CD10 antigen antibody;Common acute lymphocytic leukemia antigen antibody;DKFZp686O16152 antibody;EC 3.4.24.11 antibody;Enkephalinase antibody;EPN antibody;Membrane metallo endopeptidase (neutral endopeptidase, enkephalinase) antibody;Membrane metallo endopeptidase (neutral endopeptidase, enkephalinase, CALLA, CD10) antibody;Membrane metallo endopeptidase antibody;Membrane metallo endopeptidase variant 1 antibody;Membrane metallo endopeptidase variant 2 antibody;Membrane metalloendopeptidase antibody;Membrane metalloendopeptidase neutral endopeptidase enkephalinase antibody;Membrane metalloendopeptidase neutral endopeptidase enkephalinase CALLA CD10 antibody;Membrane metalloendopeptidase variant 1 antibody;Membrane metalloendopeptidase variant 2 antibody;MGC126681 antibody;MGC126707 antibody;MME antibody;NEP antibody;NEP_HUMAN antibody;Neprilysin antibody;neprilysin-390 antibody;neprilysin-411 antibody;Neutral endopeptidase 24.11 antibody;Neutral endopeptidase antibody;Neutral endopeptidase, membrane-associated antibody;SFE antibody;Skin fibroblast elastase antibody

SUBCELLULAR LOCATION

Cell membrane.

FUNCTION

CD10, also called the common acute lymphoblastic leukemia antigen (CALLA) and neutral endopeptidase (NEP), is a type II integral membrane glycoprotein. CD10 acts as a zinc metalloprotease that cleaves a variety of biologically active peptides including Angiotensins I and II. It is expressed on early B and T lymphoid precursors, B blasts, some granulocytes, bone marrow stromal cells and certain epithelial cells including some tumor cell lines. CD10 is used as a marker of common acute lymphocytic leukemias and some lymphomas.