FABP4 Recombinant Rabbit Monoclonal Antibody - BSA and Azide free [JM10-99] (HA750398)

UNIPROT #

P15090

PROTEIN NAME

FABP4

SYNONYMS

3T3-L1 lipid-binding protein antibody;422/aP2 antibody;A-FABP antibody;adipocyte antibody;Adipocyte lipid binding protein antibody;Adipocyte lipid-binding protein antibody;Adipocyte protein AP2 antibody;Adipocyte-type fatty acid-binding protein antibody;AFABP antibody;ALBP antibody;ALBP/Ap2 antibody;aP2 antibody;Epididymis secretory protein Li 104 antibody;FABP antibody;FABP4 antibody;FABP4_HUMAN antibody;Fatty acid binding protein 4 adipocyte antibody;Fatty acid binding protein 4 antibody;Fatty acid binding protein adipocyte antibody;Fatty acid-binding protein 4 antibody;Fatty acid-binding protein antibody;HEL S 104 antibody;Lbpl antibody;Myelin P2 protein homolog antibody;P15 antibody;P2 adipocyte protein antibody;Protein 422 antibody

SEQUENCE SIMILARITIES

Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

SUBCELLULAR LOCATION

Nucleus. Cytoplasm.

FUNCTION

Fatty acid-binding proteins, designated FABPs, are a family of homologous, cytoplasmic proteins that are expressed in a highly tissue-specific manner and play an integral role in the balance between lipid and carbohydrate metabolism. FABPs mediate fatty acid (FA) and/or hydrophobic ligand uptake, transport, and targeting within their respective tissues. The mechanisms underlying these actions can give rise to both passive diffusional uptake and protein-mediated transmembrane transport of FAs. FABPs are expressed in adipocytes (A-FABP), brain (B-FABP), epidermis (E-FABP, also designated psoriasis-associated FABP or PA-FABP), muscle and heart (H-FABP, also designated mammary-derived growth inhibitor or MDGI), intestine (I-FABP), liver (L-FABP), myelin (M-FABP) and testis (T-FABP). The human A-FABP gene is organized into 4 exons, maps to chromosome 8q21, and encodes a 132-amino acid protein. A-FABP protein comprises approximately 1% of the total cytosolic protein in human adipose tissue.