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Doublecortin Rabbit Polyclonal Antibody (IRS252RB)

Price: Regular price $278.00

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Catalog# IRS252RB

Rabbit Polyclonal to Doublecortin

Tested for

  • mIHC

Reacts with

  • Mouse

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Specifications

Product Type

Rabbit polyclonal primary

Product Name

Doublecortin Rabbit Polyclonal Antibody (IRS252RB)

Immunogen

Synthetic peptide.

Host

Rabbit

Positive Control

Mouse brain tissue.

Conjugation

Unconjugated

Clonality

Polyclonal

APPLICATION DILUTION

  • mIHC

  • 1:100

PROPERTIES

Form

Liquid

Storage Condition

Shipped at 4℃. Store at +4℃ short term (1-2 weeks). It is recommended to aliquot into single-use upon delivery. Store at -20℃ long term.

Storage Buffer

PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Purification

Protein A affinity purified.

Molecular Weight

Predicted band size: 41 kDa

Isotype

IgG

TARGET

UNIPROT #

O88809

PROTEIN NAME

Doublecortin

SYNONYMS

DBCN antibody;Dbct antibody;DC antibody;DCX antibody;DCX_HUMAN antibody;Doublecortex antibody;Doublin antibody;FLJ51296 antibody;Lis X antibody;Lis-X antibody;Lissencephalin X antibody;Lissencephalin-X antibody;Lissencephaly X linked antibody;Lissencephaly X linked doublecortin antibody;LISX antibody;Neuronal migration protein doublecortin antibody;OTTHUMP00000023859 antibody;OTTHUMP00000023860 antibody;OTTHUMP00000216315 antibody;OTTHUMP00000216316 antibody;SCLH antibody;XLIS antibody

SUBCELLULAR LOCATION

Cytoplasm, Cell projection, neuron projection.

FUNCTION

Neuronal migration protein doublecortin, also known as doublin or lissencephalin-X is a protein that in humans is encoded by the DCX gene. Doublecortin (DCX) is a microtubule-associated protein expressed by neuronal precursor cells and immature neurons in embryonic and adult cortical structures. Neuronal precursor cells begin to express DCX while actively dividing, and their neuronal daughter cells continue to express DCX for 2–3 weeks as the cells mature into neurons. Downregulation of DCX begins after 2 weeks, and occurs at the same time that these cells begin to express NeuN, a neuronal marker.

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