DDX1 Mouse Monoclonal Antibody [A10G10] (HA601332)

UNIPROT #

Q92499

PROTEIN NAME

DDX1

SYNONYMS

ATP dependent helicase DDX1 antibody;ATP-dependent RNA helicase DDX1 antibody;DBP RB antibody;DBP-RB antibody;DDX1 antibody;DDX1_HUMAN antibody;DEAD (Asp Glu Ala Asp) box polypeptide 1 antibody;DEAD box 1 antibody;DEAD box polypeptide 1 antibody;DEAD box protein 1 antibody;DEAD box protein retinoblastoma antibody;DEAD/H (Asp Glu Ala Asp/His) box polypeptide 1 antibody

SUBCELLULAR LOCATION

Nucleus, Cytoplasm, Cytoplasmic granule, cytosol, Mitochondrion.

FUNCTION

ATP-dependent RNA helicase DDX1 is an enzyme that in humans is encoded by the DDX1 gene. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein of unknown function. It shows high transcription levels in 2 retinoblastoma cell lines and in tissues of neuroectodermal origin.