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Cynomolgus PCSK9, C-His Tag Protein (HA211416)

Price: Regular price $129.00

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Catalog# HA211416

Reacts with

  • Monkey

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Product Details

Product Type

Protein

Product Name

Cynomolgus PCSK9, C-His Tag Protein (HA211416)

Predicted molecular mass

73.1 kD

Protein construction description

A DNA sequence encoding the cynomolgus PCSK9 protein (O95150-1) (Val 84-Leu 251) was expressed with a His tag at the C-terminus.

Accession

G7NVZ1

Protein construction

PCSK9 (31-692) | His

Source

HEK293

Bio Activity

Testing in progress.

Purity

>95% as determined by SDS-PAGE.

Endotoxin

Less than 1.0 EU per μg by the LAL method.

Formulation

Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4, 5% Trehalose, 5% mannitol.

Species

Monkey

Background

PCSK9 is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the endoplasmic reticulum. It is expressed mainly in liver, intestine, kidney, skin and the central nervous system. After being processed in the ER, PCSK9 co-localizes with the protein sortilin on its way through the Golgi and trans-Golgi complex. A PCSK9-sortilin interaction is proposed to be required for cellular secretion of PCSK9.

Usage Guide

Shipping

In general, recombinant proteins are provided as lyophilized powder which are shipped with blue ice. Bulk packages of recombinant proteins are provided as frozen liquid which are shipped with dry ice.

Storage

Please avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃ It is recommended that aliquot the reconstituted solution to minimize freeze-thaw cycles.

Reconstitution

Reconstitute at 250 μg/ml in sterile water.

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