Claudin 3 Recombinant Rabbit Monoclonal Antibody [PSH24-82] (HA724477)

UNIPROT #

O15551

PROTEIN NAME

Claudin 3

SYNONYMS

C7orf1 antibody;Claudin-3 antibody;Claudin3 antibody;CLD3_HUMAN antibody;CLDN 3 antibody;Cldn3 antibody;Clostridium perfringens enterotoxin receptor 2 antibody;CPE R2 antibody;CPE receptor 2 antibody;CPE-R 2 antibody;CPE-receptor 2 antibody;CPETR 2 antibody;CPETR2 antibody;HRVP 1 antibody;HRVP1 antibody;Rat ventral prostate 1 like protein antibody;Rat ventral prostate.1 protein homolog antibody;RVP1 antibody;Ventral prostate.1 like protein antibody;Ventral prostate.1 protein homolog antibody

SUBCELLULAR LOCATION

Cell junction, tight junction, Cell membrane.

FUNCTION

Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this intronless gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. It is also a low-affinity receptor for Clostridium perfringens enterotoxin, and shares aa sequence similarity with a putative apoptosis-related protein found in rat.