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CD86 Recombinant Rabbit Monoclonal Antibody [PSH25-20] (HA724514)

Price: Regular price $385.00

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Catalog# HA724514

Rabbit Monoclonal to CD86

Tested for

  • WB

  • IF-Tissue

  • IHC-P

Reacts with

  • Mouse

Recombinant production enables lot-to-lot consistency and is animal-cruelty-free

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Specifications

Product Type

Recombinant Rabbit monoclonal primary

Product Name

CD86 Recombinant Rabbit Monoclonal Antibody [PSH25-20] (HA724514)

Immunogen

Recombinant protein within mouse cd86 aa 1-265.

Host

Rabbit

Positive Control

Mouse spleen tissue lysate.

Conjugation

Unconjugated

Clonality

Monoclonal

Clone Number

PSH25-20

APPLICATION DILUTION

  • WB

  • 1:5,000

  • IF-Tissue

  • 1:200

  • IHC-P

  • 1:200-1:1,000

PROPERTIES

Form

Liquid

Storage Condition

Shipped at 4C. Store at +4C short term (1-2 weeks). Store at -20C long term.

Storage Buffer

1*PBS (pH7.4), 0.1% BSA, 40% Glycerol, 0.2% Proclean 950.

Concentration

1ug/ul

Purification

Protein A affinity purified.

Molecular Weight

Predicted band size: 35 kDa

Isotype

IgG

TARGET

UNIPROT #

P42082

PROTEIN NAME

CD86

SYNONYMS

Activation B7-2 antigen 3 antibody;Activation B7-2 antigen antibody;B-lymphocyte activation antigen B7-2 2 antibody;B-lymphocyte activation antigen B7-2 antibody;B7 2 antibody;B7 antibody;B7-2 antibody;B7.2 antibody;B70 antibody;B72 antibody;B72 antigen antibody;BU63 antibody;CD28 antigen ligand 2 2 antibody;CD28 antigen ligand 2 antibody;Cd28l2 antibody;CD28LG2 antibody;CD86 antibody;CD86 antigen (CD28 antigen ligand 2 B7 2 antigen) antibody;CD86 antigen (CD28 antigen ligand 2, B7-2 antigen) 1, 2 antibody;CD86 antigen (CD28 antigen ligand 2, B7-2 antigen) antibody;CD86 antigen antibody;CD86 molecule antibody;CD86_HUMAN antibody;CLS1 antibody;CTLA-4 counter-receptor B7.2 2 antibody;CTLA-4 counter-receptor B7.2 2, 3 antibody;CTLA-4 counter-receptor B7.2 antibody;Early T-cell costimulatory molecule 1 antibody;ETC-1 antibody;FUN 1 antibody;FUN-1 antibody;FUN1 antibody;LAB72 antibody;Ly-58 antibody;Ly58 antibody;MB7 antibody;MB7-2 antibody;Membrane glycoprotein antibody;MGC34413 antibody;T lymphocyte activation antigen CD86 precursor antibody;T-lymphocyte activation antigen CD86 antibody;TS/A-2 antibody

SUBCELLULAR LOCATION

Cell membrane

FUNCTION

Cluster of Differentiation 86 (also known as CD86 and B7-2) is a protein constitutively expressed on dendritic cells, Langerhans cells, macrophages, B-cells (including memory B-cells), and on other antigen-presenting cells. Along with CD80, CD86 provides costimulatory signals necessary for T cell activation and survival. Depending on the ligand bound, CD86 can signal for self-regulation and cell-cell association, or for attenuation of regulation and cell-cell disassociation. The CD86 gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. Alternative splicing results in two transcript variants encoding different isoforms. Additional transcript variants have been described, but their full-length sequences have not been determined.

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