CD1c Recombinant Monoclonal Antibody (IRS111RB)

UNIPROT #

P29017

PROTEIN NAME

CD1c

SYNONYMS

BDCA1 antibody;CD1 antibody;CD1A antibody;CD1c antibody;CD1c antigen antibody;CD1C antigen c polypeptide antibody;CD1c molecule antibody;CD1C_HUMAN antibody;Cortical thymocyte antigen CD1C antibody;Differentiation antigen CD1 alpha 3 antibody;R7 antibody;T cell surface glycoprotein CD1c antibody;T-cell surface glycoprotein CD1c antibody

SUBCELLULAR LOCATION

Cell membrane, Endosome membrane, Lysosome.

FUNCTION

This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene is broadly distributed throughout the endocytic system via a tyrosine-based motif in the cytoplasmic tail. Alternatively spliced transcript variants of this gene have been observed, but their full-length nature is not known.