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CD11c Recombinant Rabbit Monoclonal Antibody (IRS084)

Price: Regular price $289.00

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Catalog# IRS084

Rabbit Monoclonal to CD11c

Tested for

  • mIHC

Reacts with

  • Mouse

Recombinant production enables lot-to-lot consistency and is animal-cruelty-free

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Specifications

Product Type

Recombinant Rabbit monoclonal primary

Product Name

CD11c Recombinant Rabbit Monoclonal Antibody (IRS084)

Immunogen

Recombinant protein within mouse cd11c aa 616-936 / 1,169.

Host

Rabbit

Positive Control

Mouse spleen tissue, mouse pancreas tissue, mouse osteosarcoma subcutaneous tumor tissue.

Conjugation

Unconjugated

Clonality

Monoclonal

APPLICATION DILUTION

  • mIHC

  • 1:100

PROPERTIES

Form

Liquid

Storage Condition

Shipped at 4C. Store at +4C short term (1-2 weeks). It is recommended to aliquot into single-use upon delivery. Store at -20C long term.

Storage Buffer

1*PBS (pH7.4), 0.1% BSA, 40% Glycerol, 0.2% Proclean 950.

Purification

Protein A affinity purified.

Molecular Weight

Predicted band size: 129 kDa

Isotype

IgG

TARGET

UNIPROT #

Q9QXH4

PROTEIN NAME

CD11c

SYNONYMS

95 alpha chain antibody;95 antibody;CD 11c antibody;CD11 antigen like family member C antibody;CD11 antigen-like family member C antibody;CD11c antibody;CD11c antigen antibody;Complement component 3 receptor 4 subunit antibody;CR4 antibody;Integrin alpha X antibody;Integrin alpha X chain antibody;Integrin alpha-X antibody;Integrin aX antibody;Integrin subunit alpha X antibody;integrin, alpha X (antigen CD11C (p150), alpha polypeptide) antibody;integrin, alpha X (complement component 3 receptor 4 subunit antibody;ITAX_HUMAN antibody;ITGAX antibody;LEU M5 alpha subunit antibody;Leu M5 antibody;Leukocyte adhesion glycoprotein p150 95 alpha chain antibody;Leukocyte adhesion glycoprotein p150 antibody;Leukocyte adhesion receptor p150 95 antibody;Leukocyte adhesion receptor p150 antibody;Leukocyte surface antigen p150 95 alpha subunit antibody;Leukocyte surface antigen p150 alpha subunit antibody;Myeloid membrane antigen alpha subunit antibody;p150 95 integrin alpha chain antibody;p150 antibody;p150/95 antibody;SLEB6 antibody

SUBCELLULAR LOCATION

Membrane.

FUNCTION

CD11c is an integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles.

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