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4-Hydroxynonenal Recombinant Mouse Monoclonal Antibody [PSH23-22] (HA601598)

Price: Regular price $385.00

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Catalog# HA601598

Mouse Monoclonal to 4-Hydroxynonenal

Tested for

  • WB

  • IF-Cell

Reacts with

  • Species independent

Recombinant production enables lot-to-lot consistency and is animal-cruelty-free

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Specifications

Product Type

Recombinant Mouse monoclonal primary

Product Name

4-Hydroxynonenal Recombinant Mouse Monoclonal Antibody [PSH23-22] (HA601598)

Host

Mouse

Positive Control

HeLa treated with 0.2mg/mL 4-HNE for 30min cell lysate.

Conjugation

Unconjugated

Clonality

Monoclonal

Clone Number

PSH23-22

APPLICATION DILUTION

  • WB

  • 1:5,000

  • IF-Cell

  • 1:500

PROPERTIES

Form

Liquid

Storage Condition

Shipped at 4℃. Store at +4℃ short term (1-2 weeks). It is recommended to aliquot into single-use upon delivery. Store at -20℃ long term.

Storage Buffer

1*PBS (pH7.4), 0.1% BSA, 40% Glycerol, 0.2% Proclean 950.

Concentration

1ug/ul

Purification

Protein A affinity purified.

Isotype

IgG1

TARGET

PROTEIN NAME

4-Hydroxynonenal

SYNONYMS

(2E)-4-Hydroxy-2-nonenal;2-Nonenal, 4-hydroxy-, (2E,4R)-;4 HNE;4Hydroxynonenal;4-Hydroxynonenal;4-hydroxy-trans-2-nonenal;HNE;4-HNE;4 Hydroxynonenal

FUNCTION

4-Hydroxynonenal, or 4-hydroxy-2E-nonenal or 4-hydroxy-2-nonenal or 4-HNE or HNE, (C9H16O2), is an α,β-unsaturated hydroxyalkenal that is produced by lipid peroxidation in cells. 4-HNE is the primary α,β-unsaturated hydroxyalkenal formed in this process. It is a colorless oil. It is found throughout animal tissues, and in higher quantities during oxidative stress due to the increase in the lipid peroxidation chain reaction, due to the increase in stress events. 4-HNE has been hypothesized to play a key role in cell signal transduction, in a variety of pathways from cell cycle events to cellular adhesion.

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